[1] Ikawa M, Tanaka N, Kao WWY, Verma IM. Generation of transgenic mice using lentiviral vectors: a novel preclinical assessment of lentiviral vectors for gene therapy. Mol Ther, 2003, 8(4): 666-673.[2] Pfeifer A, Ikawa M, Dayn Y, Verma IM. Transgenesis by lentiviral vectors: lack of gene silencing in mammalian embryonic stem cells and preimplantation embryos. Proc Natl Acad Sci USA, 2002, 99(4): 2140-2145.[3] Hong S, Hwang DY, Yoon S, Isacson O, Ramezani A, Hawley RG, Kim KS. Functional analysis of various promoters in lentiviral vectors at different stages of in vitro differentiation of mouse embryonic stem cells. Mol Ther, 2007, 15(9): 1630-1639.[4] Ritchie WA, Neil C, King T, Whitelaw CBA. Transgenic embryos and mice produced from low titre lentiviral vec-tors. Transgenic Res, 2007, 16(5): 661-664.[5] Schorpp M, Jäger R, Schellander K, Schenkel J, Wagner EF, Weiher H, Angel P. The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice. Nucleic Acids Res, 1996, 24(9): 1787-1788.[6] Lois C, Hong EJ, Pease S, Brown EJ, Baltimore D. Germ-line transmission and tissue-specific expression of trans-genes delivered by lentiviral vectors. Science, 2002, 295(5556): 868-872.[7] Keating A, Horsfall W, Hawley RG, Toneguzzo F. Effect of different promoters on expression of genes introduced into hematopoietic and marrow stromal cells by electro-poration. Exp Hematol, 1990, 18(2): 99-102.[8] Muller SR, Sullivan PD, Clegg DO, Feinstein SC. Efficient transfection and expression of heterologous genes in PC12 cells. DNA Cell Biol, 1990, 9(3): 221-229.[9] Chung SM, Andersson T, Sonntag KC, Björklund L, Isacson O, Kim KS. Analysis of different promoter sys-tems for efficient transgene expression in mouse embry-onic stem cell lines. Stem Cells, 2002, 20(2): 139-145.[10] Mao G, Marotta F, Yu J, Zhou L, Yu Y, Wang L, Chui D. DNA context and promoter activity affect gene expression in lentiviral vectors. Acta Biomed, 2008, 79(3): 192-196.[11] Laegreid A, Medvedev A, Nonstad U, Bombara MP, Ranges G, Sundan A, Espevik T. Tumor necrosis factor receptor p75 mediates cell-specific activation of nuclear factor kappa B and induction of human cytomegalovirus enhancer. J Biol Chem, 1994, 269(10): 7785-7791.[12] Yew NS, Przybylska M, Ziegler RJ, Liu DP, Cheng SH. High and sustained transgene expression in vivo from plasmid vectors containing a hybrid ubiquitin promoter. Mol Ther, 2001, 4(1): 75-82.[13] Gill DR, Smyth SE, Goddard CA, Pringle IA, Higgins CF, Colledge WH, Hyde SC. Increased persistence of lung gene expression using plasmids containing the ubiquitin C or elongation factor 1α promoter. Gene Ther, 2001, 8(20): 1539-1546.[14] Guo ZS, Wang LH, Eisensmith RC, Woo SL. Evaluation of promoter strength for hepatic gene expression in vivo following adenovirus-mediated gene transfer. Gene Ther, 1996, 3(9): 802-810.[15] Löser P, Jennings GS, Strauss M, Sandig V. Reactivation of the previously silenced cytomegalovirus major immediate-early promoter in the mouse liver: involvement of NFkappaB. J Virol, 1998, 72(1): 180-190.[16] Yew NS, Wysokenski DM, Wang KX, Ziegler RJ, Marshall J, McNeilly D, Cherry M, Osburn W, Cheng SH. Optimization of plasmid vectors for high-level expression in lung epithelial cells. Hum Gene Ther, 1997, 8(5): 575-584.[17] Kuriyama S, Sakamoto T, Kikukawa M, Nakatani T, Toyokawa Y, Tsujinoue H, Ikenaka K, Fukui H, Tsujii T. Expression of a retrovirally transduced gene under control of an internal housekeeping gene promoter does not persist due to methylation and is restored partially by 5-azacytidine treatment. Gene Ther, 1998, 5(10): 1299-1305. |