奶牛重要经济性状全基因组关联分析研究进展

doi:10.3724/SP.J.1005.2012.00545

遗传 ›› 2012, Vol. 34 ›› Issue (5): 545-550.doi: 10.3724/SP.J.1005.2012.00545

奶牛重要经济性状全基因组关联分析研究进展

李聪, 孙东晓, 姜力, 刘剑锋, 张勤, 张沅, 张胜利

中国农业大学动物科技学院, 农业部畜禽遗传育种与繁殖重点实验室, 畜禽育种国家工程实验室, 北京 100193

收稿日期:2011-10-10 修回日期:2011-11-23 出版日期:2012-05-20 发布日期:2012-05-25
通讯作者: 孙东晓 E-mail:sundx@cau.edu.cn
基金资助:
国家自然科学基金项目(编号:31072016)、国家科技支撑项目(编号：2011BAD28B02)和现代农业产业技术体系北京市奶牛创新团队项目资助

Advances on genome-wide association study for economically im-portant traits in dairy cattle

LI Cong, SUN Dong-Xiao, JIANG Li, LIU Jian-Feng, ZHANG Qin, ZHANG Yuan, ZHANG Sheng-Li

National Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics, Breeding and reproduction, Ministry of Agriculture, Department of Animal Science and Technology, China Agricultural University, Beijing 100193, China

Received:2011-10-10 Revised:2011-11-23 Online:2012-05-20 Published:2012-05-25

摘要/Abstract

摘要： 产奶性状是奶牛最重要的生产性状, 随着平衡育种理念的提出和发展, 繁殖性状、体型性状、健康性状和长寿性等功能性状也逐渐被重视并纳入育种规划中。鉴定产奶性状和功能性状主效基因或遗传标记并将之应用于奶牛标记辅助选择可望加快遗传进展。随着高密度SNP标记的高通量检测技术的发展, 全基因组关联分析已成为鉴定畜禽重要经济性状基因的重要途径。文章对奶牛产奶性状和功能性状全基因组关联分析研究进展进行综述。

关键词: 产奶性状, 功能性状, 全基因组关联分析, 奶牛

Abstract: Milk performance traits have been considered as the most important production traits. With the development of balance breeding sense, much attention has been paid to the functional traits such as reproduction, type, health and longevity traits, which is put into breeding programs. Identification of major genes or genetic markers for milk production and functional traits and their applications in breeding program of dairy cattle are expected to improve the genetic progress of these traits. Occurrence of millions of SNPs in whole genome and high throughout genotyping techniques has made genome-wide association study to be an important strategy to identify genes responsible for economic traits in domestic animals. This paper reviewed the advances on genome-wide association study for milk production traits and functional traits in dairy cattle.

Key words: milk production trait, functional trait, genome-wide association study, dairy cattle

李聪，孙东晓，姜力，刘剑锋，张勤，张沅，张胜利. 奶牛重要经济性状全基因组关联分析研究进展[J]. 遗传, 2012, 34(5): 545-550.

LI Cong, SUN Dong-Xiao, JIANG Li, LIU Jian-Feng, ZHANG Qin, ZHANG Yuan, ZHANG Sheng-Li. Advances on genome-wide association study for economically im-portant traits in dairy cattle[J]. HEREDITAS, 2012, 34(5): 545-550.

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奶牛重要经济性状全基因组关联分析研究进展

Advances on genome-wide association study for economically im-portant traits in dairy cattle

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