遗传 ›› 1999, Vol. 21 ›› Issue (3): 16-730.

• 论文 • 上一篇    下一篇

中国及荷兰人群vWF基因内含子40多态性分析

郭大玮;郎海丽;徐晓莉 GUO Da-Wei;LANG Hai-Li;XU Xiao-Li      

  1. 山西医科大学法医系,太原030001 Department of Forensic Serology,Shanxi Medical University,Taiyuan030001
  • 收稿日期:1900-01-01 出版日期:1999-06-10 发布日期:1999-06-10

Human vWF Gene Intron 40 Polymorphism in Chinese and Dutch Population

  • Received:1900-01-01 Online:1999-06-10 Published:1999-06-10

摘要: 本文调查了中国汉族及荷兰高加索群体中人类vWF基因内含子40 nt 31/2 215~2 380 区域 HUMFA 31(C) 遗传多态性的基因频率及基因型频率分布。并对两群体之间的分布以拟然比方法进行比较。对9个等位基因片段测序的结果表明, 在nt 31/2 234~2 265区域也有变异存在。提示该座位当被测等位基因DNA片段长度相同时,仍可能存在遗传差异。
Abstract The allele frequencies and phenotype distribution of humanvWFgene intron 40 in the region of nt 31/2 215~2 380 (HUMFA 31(C)) were investigated in the population of the Netherlands and China. The data between two populations were compared by likelihood ratio test. Nine alleles were sequenced and the polymorphism of region of nt 31/2 234~2 265 was revealed.
  
  

关键词: vWF基因, 遗传多态性, 基因频率, Polymorphism, DNA序列 Key words vWFgene, 杂种不育性, 基因定位, 随机扩增多态性DNA, 栽培稻, 花粉不育基因座, 限制性片段长度多态性

Key words: Pollen sterility gene, Hybrid sterility, RFLP, RAPD, Molecular mapping, Oryza sativa L.