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Hereditas(Beijing) ›› 2021, Vol. 43 ›› Issue (5): 393-396.doi: 10.16288/j.yczz.21-019

• Review • Previous Articles     Next Articles

Decoding brain encoded by genome

Wei Xie1,2,3(), Chengqi Lin1, Jian Li1, Moyi Li1,2   

  1. 1. The Key Laboratory of Developmental Genes and Human Disease, School of Life Science and Technology, Southeast University, Nanjing 210096, China
    2. Department of Genetics and Development, School of Medicine, Southeast University, Nanjing 210009, China
    3. Institute for Brain and Intelligence, Southeast University, Nanjing 210096, China
  • Received:2021-01-18 Revised:2021-03-18 Online:2021-05-20 Published:2021-04-13
  • Contact: Xie Wei E-mail:wei.xie@seu.edu.cn
  • Supported by:
    Supported by the National Natural Science Foundation of China Nos(91632201);Supported by the National Natural Science Foundation of China Nos(31430035)

Abstract:

Human brain is the most complicated living organ in nature. How the human genome encodes the structure and function of brain is a fundamental question to understand the essence of mind. Currently, it is still an unsolved scientific problem requiring the further breakthrough of comprehensive technologies. Here, we summarize the recent advances in brain development/function OMICS studies, and discuss the huge challenges and prospects in understanding how brain is encoded by genome.

Key words: brain, development, genome, encode, autism