遗传 ›› 2003, Vol. 25 ›› Issue (6): 729-734.

• 论文 • 上一篇    下一篇

单核苷酸多态性及其在鸡QTL定位上的应用

聂庆华;张细权;雷明明 NIE Qing-Hua;ZHANG Xi-Quan;LEI Ming-Ming   

  1. 华南农业大学动物科学学院,广州 510642 College of Animal Science,South China Agricultural University,Guangzhou 510642,China
  • 收稿日期:1900-01-01 出版日期:2003-12-10 发布日期:2003-12-10

Single Nucleotide Polymorphism and Its Use in Chicken QTL Mapping

  • Received:1900-01-01 Online:2003-12-10 Published:2003-12-10

摘要: 单核苷酸多态性是指DNA序列上的单个碱基变异,它具有分布广、多态信息含量大、易于检测和统计分析等优点,能较好用于基因图谱构建和数量性状QTL定位研究,被称为继RFLP和微卫星标记之后的第3代基因遗传标记。本文综述了单核苷酸多态性的性质及检测技术、利用候选基因SNP进行鸡QTL定位研究的现状,并对未来SNP的应用前景进行了展望。Abstract:Single nucleotide polymorphism (SNP) refers to the change of single nucleotide in DNA sequence.Because of its high density in genomes and easy in detection and analysis statistically,SNP can be used in genetic linkage map construction and QTL mapping.Here,the characters and detecting technology of SNP,as well as the status and foreground of the use of candidate gene SNP in chicken QTL mapping are introduced.

关键词: 遗传标记, chicken, QTL定位
Key words,
单核苷酸多态性(SNP),