遗传 ›› 2002, Vol. 24 ›› Issue (2): 211-213.
刘桂兰;蒋思文;熊远著;屈彦纯 LIU Gui-lan;JIANG Si-wen;XIONG Yuan-zhu;QU Yan-chun
摘要： 胰岛素样生长因子（insulin-like growth factor,IGF）是一类多功能细胞增殖调控因子，因其化学结构与胰岛素相似而得名，IGF2是一个由67个氨基酸组成的蛋白质，它在胎儿发育、肿瘤细胞增殖、肌肉生长等方面具有重要的调控作用。本文主要论述了IGF2的基因结构、遗传方式，以及与印迹表达、肿瘤发生、肌纤维增殖和生长发育有关的生物学作用。
Abstract:Insulin-like growth factor (IGF) is multiple proliferation controlling factor of cells,and it gets this name according to its similarity to insulin.IGF2 is a single chain protein of 67 amino acids,which is probably required for normal fetal growth and development.In this article,we discussed the gene structure ,ways of its heredity ,and biological effects concerning imprinting,tumor development,muscle forming and individual growing of IGF2.
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