灯刷染色体的研究进展及其在遗传学教学中的思考

doi:10.16288/j.yczz.15-417

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HEREDITAS(Beijing) ›› 2016, Vol. 38 ›› Issue (2): 170-177.doi: 10.16288/j.yczz.15-417

• Technique and Method • Previous Articles Next Articles

Research progress in lampbrush chromosomes and some suggestions for their use in genetics teaching

Fanguo Chen^{1, 2}, Qingqing Li²

1. Genetic Teaching and Research Group, School of Life Science, Shandong University, Jinan 250100, China;
2. The Key Laboratory of Plant Cell Engineering and Germplasm Innovation, Ministry of Education, School of Life Science, Shandong University, Jinan 250100, China

Received:2015-10-08 Revised:2015-11-04 Online:2016-02-20 Published:2015-12-21

Abstract

Abstract: Lampbrush chromosomes (LBCs) are transient giant transcripts that exist at the diplotene stage of the first meiotic division in female gametocytes of almost all animals except mammals. LBCs are named for their lampbrush-like structure, however, they received the lowest research attention in studies of three classical cytogenetic chromosomes. They have been excellent models for studying the structure, organization, transcription, and transcriptional processing of chromosomes during meiosis. Here we briefly summarized these studies and LBCs forming mechanism and also discussed their possible functions, such as providing enough transcriptional products for embryonic development by oocytes LBCs or polyploidy demonstrated by previous reports. Finally, we discussed the possibility of introducing this typical case into our genetics teaching to inspire students' interest in genetics.

Key words: genetics, cytogenetics, lampbrush chromosomes (LBCs), research progress, genetics teaching

Fanguo Chen, Qingqing Li. Research progress in lampbrush chromosomes and some suggestions for their use in genetics teaching[J]. HEREDITAS(Beijing), 2016, 38(2): 170-177.

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