[1] | Zarrei M, MacDonald JR, Merico D, Scherer SW. A copy number variation map of the human genome. Nat Rev Genet, 2015, 16(3): 172-183. | [2] | Stranger BE, Forrest MS, Dunning M, Ingle CE, Beazley C, Thorne N, Redon R, Bird CP, de Grassi A, Lee C, Tyler-Smith C, Carter N, Scherer SW, Tavare S, Deloukas P, Hurles ME, Dermitzakis ET. Relative impact of nucleotide and copy number variation on gene expression phenotypes. Science, 2007, 315(5813): 848-853. | [3] | Redon R, Ishikawa S, Fitch KR, Feuk L, Perry GH, Andrews TD, Fiegler H, Shapero MH, Carson AR, Chen WW, Cho EK, Dallaire S, Freeman JL, González JR, Gratacòs M, Huang J, Kalaitzopoulos D, Komura D, MacDonald JR, Marshall CR, Mei R, Montgomery L, Nishimura K, Okamura K, Shen F, Somerville MJ, Tchinda J, Valsesia A, Woodwark C, Yang FT, Zhang JJ, Zerjal T, Zhang J, Armengol L, Conrad DF, Estivill X, Tyler-Smith C, Carter NP, Aburatani H, Lee C, Jones KW, Scherer SW, Hurles ME. Global variation in copy number in the human genome. Nature, 2006, 444(7118): 444-454. | [4] | Maillard AM, Ruef A, Pizzagalli F, Migliavacca E, Hippolyte L, Adaszewski S, Dukart J, Ferrari C, Conus P, M?nnik K, Zazhytska M, Siffredi V, Maeder P, Kutalik Z, Kherif F, Hadjikhani N, 16p11.2 European Consortium, Beckmann JS, Reymond A, Draganski B, Jacquemont S. The 16p11.2 locus modulates brain structures common to autism, schizophrenia and obesity. Mol Psychiatry, 2015, 20(1): 140-147. | [5] | Horev G, Ellegood J, Lerch JP, Son YEE, Muthuswamy L, Vogel H, Krieger AM, Buja A, Henkelman RM, Wigler M, Mills AA. Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism. Proc Natl Acad Sci USA, 2011, 108(41): 17076-17081. | [6] | Cooper GM, Coe BP, Girirajan S, Rosenfeld JA, Vu T, Baker C, Williams C, Stalker H, Hamid R, Hannig V, Abdel-Hamid H, Bader P, McCracken E, Niyazov D, Leppig K, Thiese H, Hummel M, Alexander N, Gorski J, Kussmann J, Shashi V, Johnson K, Rehder C, Ballif B C, Shaffer L G, Eichler EE. A copy number variation morbidity map of developmental delay. Nat Genet, 2011, 43(9): 838-846. | [7] | de Koning APJ, Gu WJ, Castoe TA, Batzer MA, Pollock DD. Repetitive elements may comprise over two-thirds of the human genome. PLoS Genet, 2011, 7(12): e1002384. | [8] | Coufal NG, Garcia-Perez JL, Peng GE, Yeo GW, Mu YL, Lovci MT, Morell M, O'Shea KS, Moran JV, Gage FH. L1 retrotransposition in human neural progenitor cells. Nature, 2009, 460(7259): 1127-1131. | [9] | Gerstein MB, Bruce C, Rozowsky JS, Zheng DY, Du J, Korbel JO, Emanuelsson O, Zhang ZD, Weissman S, Snyder M. What is a gene, post-ENCODE? History and updated definition. Genome Res, 2007, 17(6): 669-681. | [10] | Shapiro JA, Von Sternberg R. Why repetitive DNA is essential to genome function. Biol Rev Camb Philos Soc, 2005, 80(2): 227-250. | [11] | Cournac A, Koszul R, Mozziconacci J. The 3D folding of metazoan genomes correlates with the association of similar repetitive elements. Nucleic Acids Res, 2016 |
[1] |
Bingzheng Wang, Chao Zhang, Jiali Zhang, Jin Sun.
Conditional editing of the Drosophila melanogaster genome using single transcripts expressing Cas9 and sgRNA
[J]. Hereditas(Beijing), 2023, 45(7): 593-601.
|
[2] |
Meizhen Liu, Liren Wang, Yongmei Li, Xueyun Ma, Honghui Han, Dali Li.
Generation of genetically modified rat models via the CRISPR/Cas9 technology
[J]. Hereditas(Beijing), 2023, 45(1): 78-87.
|
[3] |
Xiaojun Zhang, Kun Xu, Juncen Shen, Lu Mu, Hongrun Qian, Jieyu Cui, Baoxia Ma, Zhilong Chen, Zhiying Zhang, Zehui Wei.
A CRISPR/Cas9-Gal4BD donor adapting system for enhancing homology-directed repair
[J]. Hereditas(Beijing), 2022, 44(8): 708-719.
|
[4] |
Chong Zhang, Zixuan Wei, Min Wang, Yaosheng Chen, Zuyong He.
Editing MC1R in human melanoma cells by CRISPR/Cas9 and functional analysis
[J]. Hereditas(Beijing), 2022, 44(7): 581-590.
|
[5] |
Yao Liu, Xianhui Zhou, Shuhong Huang, Xiaolong Wang.
Prime editing: a search and replace tool with versatile base changes
[J]. Hereditas(Beijing), 2022, 44(11): 993-1008.
|
[6] |
Yuting Han, Bowen Xu, Yutong Li, Xinyi Lu, Xizhi Dong, Yuhao Qiu, Qinyun Che, Ruibao Zhu, Li Zheng, Xiaochen Li, Xu Si, Jianquan Ni.
The cutting edge of gene regulation approaches in model organism Drosophila
[J]. Hereditas(Beijing), 2022, 44(1): 3-14.
|
[7] |
Guangwu Yang, Yuan Tian.
The F-box gene Ppa promotes lipid storage in Drosophila
[J]. Hereditas(Beijing), 2021, 43(6): 615-622.
|
[8] |
Dingwei Peng, Ruiqiang Li, Wu Zeng, Min Wang, Xuan Shi, Jianhua Zeng, Xiaohong Liu, Yaoshen Chen, Zuyong He.
Editing the cystine knot motif of MSTN enhances muscle development of Liang Guang Small Spotted pigs
[J]. Hereditas(Beijing), 2021, 43(3): 261-270.
|
[9] |
Na Wang, Zhilian Jia, Qiang Wu.
RFX5 regulates gene expression of the Pcdhα cluster
[J]. Hereditas(Beijing), 2020, 42(8): 760-774.
|
[10] |
Guoling Li, Shanxin Yang, Zhenfang Wu, Xianwei Zhang.
Recent developments in enhancing the efficiency of CRISPR/Cas9- mediated knock-in in animals
[J]. Hereditas(Beijing), 2020, 42(7): 641-656.
|
[11] |
Yingnan Chen, Jing Lu.
Application of CRISPR/Cas9 mediated gene editing in trees
[J]. Hereditas(Beijing), 2020, 42(7): 657-668.
|
[12] |
Siyuan Liu, Guoqiang Yi, Zhonglin Tang, Bin Chen.
Progress on genome-wide CRISPR/Cas9 screening for functional genes and regulatory elements
[J]. Hereditas(Beijing), 2020, 42(5): 435-443.
|
[13] |
Liwen Bao, Yiye Zhou, Fanyi Zeng.
Advances in gene therapy for β-thalassemia and hemophilia based on the CRISPR/Cas9 technology
[J]. Hereditas(Beijing), 2020, 42(10): 949-964.
|
[14] |
Minting Lin, Lulu Lai, Miao Zhao, Biwei Lin, Xiangping Yao.
Construction of a striatum-specific Slc20a2 gene knockout mice model by CRISPR/Cas9 AAV system
[J]. Hereditas(Beijing), 2020, 42(10): 1017-1027.
|
[15] |
Peifeng Liu, Qiang Wu.
Probing 3D genome by CRISPR/Cas9
[J]. Hereditas(Beijing), 2020, 42(1): 18-31.
|
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
|
|
|