遗传 ›› 1998, Vol. 20 ›› Issue (1): 14-15.
李永全; 周汝滨; 郑克勤; 潘超仁; 廖霞; 陈小萍 LI Yong-Quan;ZHOU Ru-Bin;ZHENG Ke-Qin;PAN Chao-Ren;LIAO Xia;CHEN Xiao-Ping
摘要: 一个13/21染色体罗伯逊易位家系中, 易位染色体携带者4人,易位型先天愚
型患者3人,易位染色体至少已经遗传了4代。该家系中有同性双生子的聚集现象。讨论
了罗伯逊易位的遗传机理。
Abstract:A pedigree with 13/21 robertsonian translocation was reported.There were four carriers and three patients with Downs syndrome in the padigree.The Robertsonian chromosome translocation had been transmitted at leart for four generations.A family aggregation of monozygotic twines was found in this pedigree too.The inheritance principle of robertsonian translocation was discussed and that the origin of monozygotic twins may be genetically involved were considered.