[1] | McCLINTOCK B . The origin and behavior of mutable loci in maize. Proc Natl Acad Sci USA, 1950,36(6):344-355. | [2] | Biémont C, Vieira C . Genetics: junk DNA as an evolutionary force. Nature, 2006,443(7111):521-524. | [3] | Morrish TA, Gilbert N, Myers JS, Vincent BJ, Stamato TD, Taccioli GE, Batzer MA, Moran JV . DNA repair mediated by endonuclease-independent LINE-1 retrotransposition. Nat Genet, 2002,31(2):159-165. | [4] | Gasior SL, Wakeman TP, Xu B, Deininger PL . The human LINE-1 retrotransposon creates DNA double-strand breaks. J Mol Biol, 2006, 357(5):1383-1393. | [5] | Chen Y, Pane A, Schupbach T . Cutoff and aubergine mutations result in retrotransposon upregulation and checkpoint activation inDrosophila. Curr Biol, 2007,17(7):637-642. | [6] | Han YN, Li Y, Xia SQ, Zhang YY, Zheng JH, Li W . PIWI proteins and PIWI-interacting RNA: Emerging roles in cancer . Cell Physiol Biochem, 2017,44(1):1-20. | [7] | Ye ZJ, Liu QP, Cen S, Li XY . The function of LINE-1 encoded reverse transcriptase in tumorigenesis. Hereditas (Beijing), 2017,39(5):368-376. | [7] | 叶仲杰, 刘启鹏, 岑山, 李晓宇 . LINE-1编码的逆转录酶在肿瘤形成过程中的作用. 遗传, 2017,39(5):368-376. | [8] | Liu Q, Wang JH, Li XY, Cen S . The connection between LINE-1 retrotransposition and human tumorigenesis . Hereditas (Beijing), 2016,38(2):93-102. | [8] | 刘茜, 王瑾晖, 李晓宇, 岑山 . 逆转录转座子LINE-1与肿瘤的发生和发展. 遗传, 2016,38(2):93-102. | [9] | Malone CD, Hannon GJ . Small RNAs as guardians of the genome. Cell, 2009,136(4):656-668. | [10] | Moyano M , Stefani G. piRNA involvement in genome stability and human cancer. J Hematol Oncol, 2015,8:38. | [11] | Lau NC, Seto AG, Kim J, Kuramochi-Miyagawa S, Nakano T, Bartel DP, Kingston RE . Characterization of the piRNA complex from rat testes. Science, 2006,313(5785):363-367. | [12] | Ernst C, Odom DT, Kutter C . The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity. Nat Commun, 2017. 8(1):1411. | [13] | Shen EZ, Chen H, Ozturk AR, Tu S, Shirayama M, Tang W, Ding YH, Dai SY, Weng Z, Mello CC . Identification of piRNA binding sites reveals the argonaute regulatory landscape of the C. elegans germline. Cell, 2018, 172(5): 937-951. e918. | [14] | Zhang D, Tu S, Stubna M, Wu WS, Huang WC, Weng Z, Lee HC . The piRNA targeting rules and the resistance to piRNA silencing in endogenous genes. Science, 2018,359(6375):587-592. | [15] | Watanabe T, Tomizawa S, Mitsuya K, Totoki Y, Yamamoto Y, Kuramochi-Miyagawa S, Iida N, Hoki Y, Murphy PJ, Toyoda A, Gotoh K, Hiura H, Arima T, Fujiyama A, Sado T, Shibata T, Nakano T, Lin H, Ichiyanagi K, Soloway PD, Sasaki H . Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Science, 2011,332(6031):848-852. | [16] | Gou LT, Kang JY, Dai P, Wang X, Li F, Zhao S, Zhang M, Hua MM, Lu Y, Zhu Y, Li Z, Chen H, Wu LG, Li D, Fu XD, Li J, Shi HJ, Liu MF . Ubiquitination-deficient mutations in human Piwi cause male infertility by impairing histone-to-protamine exchange during spermiogenesis. Cell, 2017, 169(6): 1090-1104. e1013. | [17] | Le Thomas A, Rogers AK, Webster A, Marinov GK, Liao SE, Perkins EM, Hur JK, Aravin AA, Tóth KF . Piwi induces piRNA-guided transcriptional silencing and establishment of a repressive chromatin state. Genes Dev, 2013,27(4):390-399. | [18] | Sienski G, D?nertas D, Brennecke J . Transcriptional silencing of transposons by Piwi and maelstrom and its impact on chromatin state and gene expression. Cell, 2012,151(5):964-980. | [19] | Brower-Toland B, Findley SD, Jiang L, Liu L, Yin H, Dus M, Zhou P, Elgin SC, Lin H . Drosophila PIWI associates with chromatin and interacts directly with HP1a. Genes Dev, 2007,21(18):2300-2311. | [20] | Huang XA, Yin H, Sweeney S, Raha D, Snyder M, Lin H . A major epigenetic programming mechanism guided by piRNAs. Dev Cell, 2013,24(5):502-516. | [21] | Findley SD, Tamanaha M, Clegg NJ, Ruohola-Baker H . Maelstrom, a Drosophila spindle-class gene, encodes a protein that colocalizes with Vasa and RDE1/AGO1 homolog, Aubergine, in nuage . Development, 2003,130(5):859-871. | [22] | Lim AK, Kai T . Unique germ-line organelle, nuage, functions to repress selfish genetic elements in Drosophila melanogaster. Proc Natl Acad Sci USA, 2007,104(16):6714-6719. | [23] | Iwasaki YW, Murano K, Ishizu H, Shibuya A, Iyoda Y, Siomi MC, Siomi H, Saito K . Piwi modulates chromatin accessibility by regulating multiple factors including histone H1 to repress transposons. Mol Cell, 2016,63(3):408-419. | [24] | Newkirk SJ, Lee S, Grandi FC, Gaysinskaya V, Rosser JM, Vanden Berg N, Hogarth CA, Marchetto MCN, Muotri AR, Griswold MD, Ye P, Bortvin A, Gage FH, Boeke JD, An W . Intact piRNA pathway prevents L1 mobilization in male meiosis. Proc Natl Acad Sci USA, 2017,114(28):E5635-E5644. | [25] | Aravin AA, Bourc'his D . Small RNA guides for de novo DNA methylation in mammalian germ cells. Genes Dev, 2008,22(8):970-975. | [26] | Aravin AA, Sachidanandam R, Bourc'his D, Schaefer C, Pezic D, Toth KF, Bestor T, Hannon GJ . A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice. Mol Cell, 2008,31(6):785-799. | [27] | Aravin AA, Hannon GJ, Brennecke J . The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race. Science, 2007,318(5851):761-764. | [28] | Saito K, Inagaki S, Mituyama T, Kawamura Y, Ono Y, Sakota E, Kotani H, Asai K, Siomi H, Siomi MC . A regulatory circuit for piwi by the large Maf gene traffic jam in Drosophila. Nature, 2009,461(7268):1296-1299. | [29] | Brennecke J, Aravin AA, Stark A, Dus M, Kellis M, Sachidanandam R, Hannon GJ . Discrete small RNA- generating loci as master regulators of transposon activity in Drosophila. Cell, 2007,128(6):1089-1103. | [30] | Klenov MS, Sokolova OA, Yakushev EY, Stolyarenko AD, Mikhaleva EA, Lavrov SA, Gvozdev VA . Separation of stem cell maintenance and transposon silencing functions of Piwi protein. Proc Natl Acad Sci USA, 2011,108(46):18760-18765. | [31] | Klenov MS, Lavrov SA, Stolyarenko AD, Ryazansky SS, Aravin AA, Tuschl T, Gvozdev VA . Repeat-associated siRNAs cause chromatin silencing of retrotransposons in the Drosophila melanogaster germline. Nucleic Acids Res, 2007,35(16):5430-5438. | [32] | Wang SH, Elgin SC . Drosophila Piwi functions downstream of piRNA production mediating a chromatin-based transposon silencing mechanism in female germ line. Proc Natl Acad Sci USA, 2011,108(52):21164-21169. | [33] | Schoeberl UE, Mochizuki K . Keeping the soma free of transposons: programmed DNA elimination in ciliates. J Biol Chem, 2011,286(43):37045-37052. | [34] | Mochizuki K, Gorovsky MA . A Dicer-like protein in Tetrahymena has distinct functions in genome rearrangement, chromosome segregation, and meiotic prophase. Genes Dev, 2005,19(1):77-89. | [35] | Mochizuki K, Fine NA, Fujisawa T, Gorovsky MA . Analysis of a piwi-related gene implicates small RNAs in genome rearrangement in Tetrahymena. Cell, 2002,110(6):689-699. | [36] | Bracht JR, Fang W, Goldman AD, Dolzhenko E, Stein EM, Landweber LF . Genomes on the edge: programmed genome instability in ciliates. Cell, 2013,152(3):406-416. | [37] | Fang W, Wang X, Bracht JR, Nowacki M, Landweber LF . Piwi-interacting RNAs protect DNA against loss during Oxytricha genome rearrangement. Cell, 2012,151(6):1243-1255. | [38] | Boldrin F, Santovito G, Irato P, Piccinni E . Metal interaction and regulation of Tetrahymena pigmentosa metallothionein genes. Protist, 2002,153(3):283-291. | [39] | Prescott DM, Ehrenfeucht A, Rozenberg G . Template- guided recombination for IES elimination and unscrambling of genes in stichotrichous ciliates. J Theor Biol, 2003,222(3):323-330. | [40] | Angeleska A, Jonoska N, Saito M, Landweber LF . RNA-guided DNA assembly. J Theor Biol, 2007,248(4):706-720. | [41] | Nowacki M, Vijayan V, Zhou Y, Schotanus K, Doak TG, Landweber LF . RNA-mediated epigenetic programming of a genome-rearrangement pathway. Nature, 2008,451(7175):153-158. | [42] | Teixeira FK, Okuniewska M, Malone CD, Coux RX, Rio DC , Lehmann R. piRNA-mediated regulation of transposon alternative splicing in the soma and germ line. Nature, 2017,552(7684):268-272. | [43] | Lenart P, Novak J, Bienertova-Vasku J . PIWI-piRNA pathway: Setting the pace of aging by reducing DNA damage. Mech Ageing Dev, 2018, doi: 10.1016/j.mad. 2018.03.009. | [44] | Liu X, Sun Y, Guo J, Ma H, Li J, Dong B, Jin G, Zhang J, Wu J, Meng L, Shou C . Expression of hiwi gene in human gastric cancer was associated with proliferation of cancer cells. Int J Cancer, 2006,118(8):1922-1929. | [45] | Zhao YM, Zhou JM, Wang LR, He HW, Wang XL, Tao ZH, Sun HC, Wu WZ, Fan J, Tang ZY, Wang L . HIWI is associated with prognosis in patients with hepatocellular carcinoma after curative resection. Cancer, 2012,118(10):2708-2717. |
|