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HEREDITAS ›› 2011, Vol. 33 ›› Issue (10): 1102-1112.doi: 10.3724/SP.J.1005.2011.01102

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Synthetic biology and rearrangements of microbial genetic material

LIANG Quan-Feng1,2, WANG Qian2, QI Qing-Sheng1,2   

  1. 1. State Key Laboratory of Microbial Technology, Shandong University, Jinan 250100, China 2. National Glycoengineering Research Center, Shandong University, Jinan 250100, China
  • Received:2011-04-24 Revised:2011-06-30 Online:2011-10-20 Published:2011-10-25

Abstract: As an emerging discipline, synthetic biology has shown great scientific values and application prospects. Although there have been many reviews of various aspects on synthetic biology over the last years, this article, for the first time, attempted to discuss the relationship and difference between microbial genetics and synthetic biology. We summarized the recent development of synthetic biology in rearranging microbial genetic materials, including synthesis, design and reduction of genetic materials, standardization of genetic parts and modularization of genetic circuits. The relationship between synthetic biology and microbial genetic engineering was also discussed in the paper.

Key words: synthetic biology, genetics, microorganism, genetic material, microbial genetic engineering