遗传 ›› 2017, Vol. 39 ›› Issue (7): 568-575.doi: 10.16288/j.yczz.17-067

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植物Hippo信号通路研究进展

张平平(),佟鑫,张天乐,黎子琛,龚清秋()   

  1. 南开大学生命科学学院,天津市蛋白质科学重点实验室,天津 300071
  • 收稿日期:2017-02-28 修回日期:2017-04-28 出版日期:2017-07-20 发布日期:2017-05-08
  • 作者简介:张平平,硕士研究生,专业方向:植物生理与分子生物学。E-mail: zhangppsmile@163.com|龚清秋,博士,副教授,研究方向:胞内运输与植物发育。E-mail: gongq@nankai.edu.cn
  • 基金资助:
    国家自然科学基金项目(31671419);南开大学中央高校基本科研业务费(63161201)

The emerging Hippo signaling pathway in plants

Zhang Pingping(),Tong Xin,Zhang Tianle,Li Zichen,Gong Qingqiu()   

  1. Tianjin Key Laboratory of Protein Sciences, College of Life Sciences, Nankai University, Tianjin 300071, China
  • Received:2017-02-28 Revised:2017-04-28 Online:2017-07-20 Published:2017-05-08
  • Supported by:
    the National Natural Science Foundation of China(31671419);the Fundamental Research Funds of the Central Universities(63161201)

摘要:

植物器官大小如何决定是发育生物学的基本问题之一。Hippo信号通路是动物中最重要的负调控器官大小的信号通路。近期研究表明,植物中可能也存在Hippo信号通路。本文回顾了植物中已经发现的两个Hippo信号通路的核心蛋白——Ste20/Hippo同源蛋白SIK1与MOB1/Mats同源蛋白MOB1,着重论述了SIK1和MOB1在调控植物生长发育中的作用,并对未来建立一条完整的植物Hippo信号通路进行了展望。

关键词: Hippo信号通路, SIK1, MOB1, 器官大小, 细胞分裂, 细胞延展

Abstract:

How the organ size is determined is a fundamental question in developmental biology. The metazoan Hippo signaling pathway is well established to negatively regulate organ sizes. Recent studies in plants have started to shape an emerging Hippo signaling pathway. In this review, we summarize the studies in the past decade on the two known components of plant Hippo signaling pathway, the Ste20/Hippo homolog SIK1, and the MOB1/Mats homolog MOB1, with a focus on their developmental functions. Then we envision future discoveries that may shape a complete Hippo signaling pathway in plants.

Key words: Hippo signaling pathway, serine/threonine kinase 1 (SIK1), MOB1, organ size, cell division, cell expansion