遗传 ›› 2024, Vol. 46 ›› Issue (4): 346-354.doi: 10.16288/j.yczz.24-017
• 遗传学教学 • 上一篇
收稿日期:
2024-01-15
修回日期:
2024-02-18
出版日期:
2024-04-20
发布日期:
2024-03-04
作者简介:
毛春晓,博士,讲师,研究方向:表观遗传学。E-mail: cxmao@bio.ecnu.edu.cn.
基金资助:
Received:
2024-01-15
Revised:
2024-02-18
Published:
2024-04-20
Online:
2024-03-04
Supported by:
摘要:
在遗传学课程教学中,红绿色盲是X连锁隐性遗传的典型案例。然而红绿色盲只是比较常见的色觉障碍,还有其他临床分型。不同的色盲遗传方式可能不同,致病基因也不同。近年来,关于色盲的致病基因、分子机制、基因治疗等方面取得了很大进展,相关研究成果可以作为很好的素材在遗传学教学中进行使用。本文阐述了基于色盲的遗传学教学素材的挖掘及其在本校遗传学课程中“绪论”“遗传的细胞和分子基础”“伴性遗传”“染色体畸变”“基因突变”“遗传学进展”等章节教学中的应用。通过课堂教授与问答,辅以课后文献检索与阅读,使学生在更好掌握遗传学基本内容的基础上,能拓宽遗传学学术视野,激发学习兴趣。
毛春晓. 基于色盲遗传学教学素材的挖掘及其在教学中应用[J]. 遗传, 2024, 46(4): 346-354.
Chunxiao Mao. The construction of genetics teaching resources related to colour blindness and their application in genetics teaching[J]. Hereditas(Beijing), 2024, 46(4): 346-354.
表1
先天性色觉缺陷的主要类型"
按严重程度划分 | 类型 | 参考文献 |
---|---|---|
异常三色视觉 (anomalous trichromacy) | 红色弱(protanomaly) | [ |
绿色弱(deuteranomaly) | [ | |
蓝黄色弱(tritanomaly) | [ | |
双色视觉 (dichromacy) | 红色盲(protanopia) | [ |
绿色盲(deuteranopia) | [ | |
蓝黄色盲(tritanopia) | [ | |
单色视觉 (monochromacy) | 红锥单色视 (red-cone monochromacy) | [ |
绿锥单色视 (green-cone monochromacy) | [ | |
蓝锥单色视 (blue-cone monochromacy) | [ | |
全色盲 (achromatopsia) | 视杆细胞单色视 (rod monochromacy) | [ |
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