遗传 ›› 2006, Vol. 28 ›› Issue (8): 1002-1008.

• 专论与综述 • 上一篇    下一篇

鸡基因组计划及在遗传学研究中的应用

赵心怡1 , 杨 威2 , 张 勇2 , 朱大海1, 2   

  1. 1.哈尔滨工业大学生命科学与工程系,分子与细胞发育生物学实验室, 哈尔滨 150001;2.中国协和医科大学 基础医学院生物化学与分子生物学系,医学分子生物学国家重点实验室, 北京 100005

  • 收稿日期:2005-07-16 修回日期:2005-08-29 出版日期:2006-08-10 发布日期:2006-08-10
  • 通讯作者: 赵心怡

The Chicken Genome Project and its Application in the Research Work of Genetics

ZHAO Xin-Yi 1, YANG Wei 2, ZHANG Yong 2, ZHU Da-Hai 1,2

  

  1. 1. Department of Life Science and Engineering, Molecular and Cellular Development Biology Laboratory, Harbin Institute of Technology, Harbin 150001,China;2. Department of Biochemistry and National Laboratory of Medical Molecular Biology, School of Basic Medical Sciences, Peking Union Medical School, Beijing 100005, China

  • Received:2005-07-16 Revised:2005-08-29 Online:2006-08-10 Published:2006-08-10

摘要: 鸡,以其独特的生物学特性,成为研究许多生物学问题的重要模式生物。而在长期选育中形成的肉鸡和蛋鸡两大品系则是研究许多遗传性状的分子机制的理想模型。鸡基因组计划的完成,极大推动了以鸡作为模式生物的研究与开发工作。本文重点介绍了鸡基因组学的研究进展,和利用基因组相关信息对鸡的不同品系的数量性状进行遗传学研究的方法策略;并阐明了以鸡作为模式生物,利用基因组学的信息进行发育和遗传学研究的广阔前景。

关键词: 鸡, 基因组, 肉鸡和蛋鸡, 基因组作图

Abstract: Chicken is an important animal modal for studying all sorts of biological problems due to its unique biological features. The two strains, egg laying (layer) and meat production (Broiler) which were generated from selective breeding, come to be ideal models for understanding the molecular mechanisms underlying different phenotypes. The chicken Genome Project provides large amount of information for the research work with chicken as the model. This review summaries the development of the Chicken Genome Project, as well as the strategies that research for the quantitative traits of different chicken strains using the information of chicken genome. And we also elucidate the perspective of the developmental and genetic research work assisted by the chicken genome information and with chicken as the animal modal.

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