遗传 ›› 2006, Vol. 28 ›› Issue (2): 236-242.

• 专论与综述 • 上一篇    下一篇

染色体领域的研究及其进展

傅美丽;  李宗芸; 胡方方; 黄淑峰   

  1. 徐州师范大学生命科学学院,徐州 221116
  • 收稿日期:2005-03-19 修回日期:2005-06-30 出版日期:2006-02-10 发布日期:2006-02-10
  • 通讯作者: 李宗芸

The Progress and Research of Chromosome Territories(CTs)

FU Mei-Li,  LI Zong-Yun, HU Fang-Fang, HUANG Shu- Feng   

  1. School of Life Science, Xuzhou Normal Univeisity, Xuzhou 221116, China
  • Received:2005-03-19 Revised:2005-06-30 Online:2006-02-10 Published:2006-02-10

摘要:

 间期核中的染色体并不是散乱分布的,而是每条染色体占据了一块特定的核区域,即染色体领域(chromosome territory, CTs),染色体领域在间期核中的排列与定位是经过严格组织的,并具有一定的动力学特征,染色体领域的这些严格的定位和空间组织与基因的表达调控密切相关。文章综述了这几个方面的研究进展。
 
 
 

关键词: 染色体领域, 间期核, 拉布尔分布, 转录

Abstract: Chromosomes are non-randomly distributed in interphase nucleus, and each chromosome occupies a distinct domain in the chromosome territories (CTs), the positioning and arrangement of CTs are well-organized, at the same time, the chromosome territories have definite dynamics characteristics, the strict positioning and spatial organization of chromosome territories are closely related with gene expression regulation. This paper reviewed progress in these respects.

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