遗传 ›› 2019, Vol. 41 ›› Issue (10): 928-938.doi: 10.16288/j.yczz.19-147

• 综述 • 上一篇    下一篇

山羊基因组研究进展

王凤红1,张磊1,李晓凯1,范一星1,乔贤1,龚高1,严晓春1,张令天1,王志英1,王瑞军1,2,3,4,刘志红1,2,3,王志新1,2,3,何利兵4,张燕军1,2,3,李金泉1,2,3,赵艳红1(),苏蕊1,2,3()   

  1. 1. 内蒙古农业大学动物科学学院,呼和浩特 010018
    2. 农业部肉羊遗传育种重点实验室,呼和浩特 010018
    3. 内蒙古自治区山羊遗传育种工程技术研究中心,呼和浩特 010018
    4. 内蒙古金莱牧业科技有限责任公司,呼和浩特 010018
  • 收稿日期:2019-05-22 修回日期:2019-09-22 出版日期:2019-10-20 发布日期:2019-10-09
  • 通讯作者: 赵艳红,苏蕊 E-mail:13947196432@163.com;suruiyu@126.com
  • 作者简介:王凤红,博士研究生,研究方向:绒山羊分子遗传育种。E-mail: nmgcfwfh@163.com
  • 基金资助:
    国家自然科学基金项目编号:(31660639);国家自然科学基金项目编号:(31860637);国家自然科学基金项目编号:(31860628);国家绒毛用羊产业技术体系项目编号:(CARS-39-06);内蒙古自然科学基金项目编号:(2017MS0304);内蒙古农业大学“双一流”学科创新团队建设人才培育项目资助编号:(NDSC2018-01)

Progress in goat genome studies

Feng-hong Wang1,Lei Zhang1,Xiao-kai Li1,Yi-xing Fan1,Xian Qiao1,Gao Gong1,Xiao-chun Yan1,Ling-tian Zhang1,Zhi-ying Wang1,Rui-jun Wang1,2,3,4,Zhi-hong Liu1,2,3,Zhi-xin Wang1,2,3,Libing He4,Yanjun Zhang1,2,3,Jin-quan Li1,2,3,Yan-hong Zhao1(),Rui Su1,2,3()   

  1. 1. College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China
    2. Key Laboratory of Mutton Sheep Genetics and Breeding, Ministry of Agriculture, Hohhot 010018, China
    3. Engineering Research Center for Goat Genetics and Breeding, Inner Mongolia Autonomous Region, Hohhot 010018, China
    4. Inner Mongolia Jinlai Livestock Technology Co., Ltd, Hohhot 010018, China
  • Received:2019-05-22 Revised:2019-09-22 Online:2019-10-20 Published:2019-10-09
  • Contact: Zhao Yanhong,Su Rui E-mail:13947196432@163.com;suruiyu@126.com
  • Supported by:
    Supported by the National Natural Science Foundation of China Nos.(31660639);Supported by the National Natural Science Foundation of China Nos.(31860637);Supported by the National Natural Science Foundation of China Nos.(31860628);China Agriculture Research System No.(CARS-39-06);Inner Mongolia Natural Science Foundation No.(2017MS0304);Cultivation of Talents for "Double- first-class" Discipline Innovation Team Construction in Inner Mongolia Agricultural University No.(NDSC2018-01)

摘要:

山羊基因组是山羊品种资源保护和利用的研究依据,对培育和改良山羊品种具有重要意义。目前,随着山羊参考基因组的不断完善,在山羊起源、进化和适应性等方面的研究取得了诸多重要成果。本文详细综述了山羊基因组研究进展,主要包括山羊基因组结构、山羊基因组图谱(遗传图谱、物理图谱和比较图谱)、山羊高通量测序和山羊SNP芯片的开发及利用,以期为开展山羊基因组选择(genome selection, GS)奠定理论基础。

关键词: 山羊, 基因组结构, 基因图谱, 芯片, 基因组选择

Abstract:

The goat genome is the research basis for the protection and utilization of goat resources, which is important for breeding and improving goat breeds. At present, with the continuous improvement of goat reference genome, various important research progress in goat origin, evolution and adaptability has been achieved. In this review, we summarize the research progress in the goat genome in detail, encompassing goat genome structure, genome map (genetic, physical and comparative maps), goat high throughput sequencing and SNP chip development. We aim to provide a theoretical foundation for the development of goat genome selection.

Key words: goat, genome structure, genome map, chip, genome selection