联会复合体的组成、功能及遗传控制

doi:10.3724/SP.J.1005.2012.00167

遗传 ›› 2012, Vol. 34 ›› Issue (2): 167-176.doi: 10.3724/SP.J.1005.2012.00167

联会复合体的组成、功能及遗传控制

谢文军¹, 史典义¹, 蔡泽熙¹, 陈晓阳², 金危危¹

1. 中国农业大学国家玉米改良中心, 农业部作物遗传改良基因组研究重点实验室, 北京 100193 2. 湖南农业大学农学院, 长沙 410128

收稿日期:2011-06-13 修回日期:2011-08-15 出版日期:2012-02-20 发布日期:2012-02-25
通讯作者: 金危危 E-mail:weiweijin@cau.edu.cn
基金资助:
国家重点基础研究发展规划项目(“973计划”)(编号：2011CB944600)资助

Organization, function and genetic controlling of synaptonemal complex

XIE Wen-Jun¹, SHI Dian-Yi¹, CAI Ze-Xi¹, CHEN Xiao-Yang², JIN Wei-Wei¹

1. National Maize Improvement Center of China, Key Laboratory of Crop Genetic Improvement and Genome of Ministry of Agricul-ture, China Agricultural University, Beijing 100193, China 2. College of Agriculture, Hunan Agricultural University, Changsha 410128, China

Received:2011-06-13 Revised:2011-08-15 Online:2012-02-20 Published:2012-02-25

摘要/Abstract

摘要： 在多数有性生殖生物中, 减数分裂第一次分裂前期同源染色体间会形成一种复杂的超级蛋白结构——联会复合体(Synaptonemal complex, SC)。该结构与同源染色体间的配对、联会、交换、分离等过程密切相关。若其出现异常, 将可导致性母细胞大量凋亡, 宏观上即表现为生物个体不育。近年来, 该结构已成为减数分裂研究领域的一个热点, 但其控制机理至今所知还十分有限。文章对联会复合体的组成、功能及其遗传控制等情况进行概述, 并对其未来的研究进行探讨和展望。

关键词: 联会复合体, 同源匹配, 配对, 重组, 减数分裂, 不育

Abstract: The synaptonemal complex (SC) is a super protein lattice that connects paired homologous chromosomes in most meiotic systems. This special organization is related to the meiosis processes such as homologous chromosomes pairing, synapsis, recombination, segregation, etc. Flaws of it would lead the meiocytes to apoptosis, which contributes to sterility. In recent years, the study of this complex has been a hotspot in meiosis research, but little was known about its exact mechanism. This review summarized the organization, function, and genetics of this complex with recent advances. Prospects of its further study were also briefly discussed.

Key words: synaptonemal complex, alignment, pairing, recombination, meiosis, sterility

谢文军，史典义，蔡泽熙，陈晓阳，金危危. 联会复合体的组成、功能及遗传控制[J]. 遗传, 2012, 34(2): 167-176.

XIE Wen-Jun, SHI Dian-Yi, CAI Ze-Xi, CHEN Xiao-Yang, JIN Wei-Wei. Organization, function and genetic controlling of synaptonemal complex[J]. HEREDITAS, 2012, 34(2): 167-176.

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联会复合体的组成、功能及遗传控制

Organization, function and genetic controlling of synaptonemal complex

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