遗传 ›› 2013, Vol. 35 ›› Issue (4): 459-467.doi: 10.3724/SP.J.1005.2013.00459
李方方, 李文庆, 荆清
收稿日期:2012-05-08
修回日期:2012-08-24
出版日期:2013-04-20
发布日期:2013-04-25
通讯作者:
荆清
E-mail:qjing@sibs.ac.cn
基金资助:国家自然科学基金重点项目(编号：81130005)资助
LI Fang-Fang, LI Wen-Qing, JING Qing
Received:2012-05-08
Revised:2012-08-24
Online:2013-04-20
Published:2013-04-25
摘要： 血管发育包括血管发生和血管生成两个阶段。近年研究表明, G蛋白偶联受体广泛参与调控成血管细胞的分化、迁移和接合, 尖端细胞和柄细胞命运决定, 内皮细胞的增殖、迁移和管腔形成等多个过程。文章以血管发育中的这些关键事件为主线, 总结了G蛋白偶联受体家族成员特别是视紫红质类和卷曲类受体在调节血管发育方面的最新研究进展。文章着重介绍了斑马鱼作为模式生物在血管发育生物学研究中的独特优势, 并展望了利用斑马鱼深入开展G蛋白偶联受体相关研究的广阔前景。
李方方 李文庆 荆清. G蛋白偶联受体在血管发育中的作用[J]. 遗传, 2013, 35(4): 459-467.
LI Fang-Fang, LI Wen-Qing, JING Qing. G protein-coupled receptors in vascular development[J]. HEREDITAS, 2013, 35(4): 459-467.
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