遗传 ›› 2014, Vol. 36 ›› Issue (8): 766-778.doi: 10.3724/SP.J.1005.2014.0766
索金伟, 戴绍军
收稿日期:2014-01-22
出版日期:2014-08-20
发布日期:2013-07-19
通讯作者:
戴绍军,教授,博士生导师,研究方向：植物蛋白质组学。E-mail:daishaojun@hotmail.com
作者简介:索金伟,博士研究生,研究方向：植物蛋白质组学。E-mail: suojinwei@foxmail.com
基金资助:Jinwei Suo, Shaojun Dai
Received:2014-01-22
Online:2014-08-20
Published:2013-07-19
摘要： 花粉管极性生长受多种信号与代谢过程的调控,主要包括Rop GTPase信号途径、磷脂酰肌醇信号通路、Ca2+信号途径、肌动蛋白动态变化、囊泡运输、细胞壁重塑等,这些过程都受到蛋白质可逆磷酸化作用的调节。如：(1) Rop调节蛋白(GEF、GDI和GAP)的可逆磷酸化可以改变其活性,从而调节Rop GTPase;同时,蛋白激酶还可能作为Rop下游的效应器分子参与Rop下游信号途径的调节;(2) 蛋白质可逆磷酸化作用既能够激活/失活质膜上的Ca2+通道或Ca2+泵,又参与调节胞内贮存Ca2+的释放,从而调控花粉管尖端Ca2+梯度的形成;此外,蛋白激酶还作为Ca2+信号的感受器,磷酸化相应的靶蛋白,参与Ca2+信号下游途径的调节;(3) 肌动蛋白结合蛋白(ADF和Profilin)的活性也受到蛋白质可逆磷酸化的调节,进而调控肌动蛋白聚合与解聚之间的动态平衡;(4) 蛋白质磷酸化作用调节胞吞/胞吐相关蛋白的活性,并调控质膜的磷脂代谢,从而参与调控囊泡运输过程;(5) 胞质丝氨酸/苏氨酸蛋白激酶和蔗糖合酶的可逆磷酸化可以调节其在花粉管中的功能与分布模式,参与花粉管细胞壁重塑;(6) 转录调节蛋白与真核生物翻译起始因子的可逆磷酸化可以改变其活性,从而调控RNA转录与蛋白质合成。文章主要综述了花粉管生长过程中重要蛋白质的可逆磷酸化作用对上述关键事件的调节。
索金伟, 戴绍军. 蛋白质可逆磷酸化对花粉管生长的调控作用[J]. 遗传, 2014, 36(8): 766-778.
Jinwei Suo, Shaojun Dai. Regulation of pollen tube growth by reversible protein phosphorylation[J]. HEREDITAS(Beijing), 2014, 36(8): 766-778.
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