遗传 ›› 2012, Vol. 34 ›› Issue (6): 659-665.doi: 10.3724/SP.J.1005.2012.00659

• 综述 • 上一篇    下一篇

尼安德特人基因组学研究进展

秘彩莉, 郭光艳, 张晓, 田彦辉, 沈银柱   

  1. 河北师范大学生命科学学院, 石家庄050016
  • 收稿日期:2011-09-27 修回日期:2012-04-28 出版日期:2012-06-20 发布日期:2012-06-25
  • 通讯作者: 沈银柱 E-mail:yinzhushen@sohu.com
  • 基金资助:

    河北师范大学第十批精品课程建设项目(编号:27)和第十一批校级教学改革研究项目(编号:25)资助

Progresses on Neandertal genomics

BI Cai-Li, GUO Guang-Yan, ZHANG Xiao, TIAN Yan-Hui, SHEN Yin-Zhu   

  1. College of Life Science, Hebei Normal University, Shijiazhuang 050016, China
  • Received:2011-09-27 Revised:2012-04-28 Online:2012-06-20 Published:2012-06-25

摘要: 尼安德特人是现代人最近的旁支, 也是化石资料最丰富的古人类。在现代人起源问题的争论中, 尼安德特人对现代人是否有遗传贡献是一个焦点问题。文章综述了近年来关于尼安德特人线粒体基因组和核基因组的研究进展, 初步研究表明尼安德特人可能对现代人有遗传贡献, 这引发了人们对现代人起源问题的重新思考。藉尼人基因组研究经验进行的古人类基因组学研究将有望揭开现代人起源的谜团, 并丰富进化生物学相关领域的理论体系。

关键词: 尼安德特人, 基因组学, 现代人起源

Abstract: Neandertal is our closest known relative and also an archaic hominid reserving the richest fossils. Whether the Neandertals exchanged their DNA with modern human or not is a matter of debate on the modern human origin. The progresses on the mitochondrial and nuclear genomes of Neandertals in recent years were reviewed in this paper. Recent study has revealed possible genetic contribution of Neandertals to the modern human to some extent, which arose the rethinking of modern human origin. The experiences gained in the research on Neandertals will benefit the study on archaic hominids, unravel the mystery of modern human origin, and enrich the relative theoretical systems in evolutionary biological field.

Key words: genomics, modern human origin, Neandertal