水稻稻瘟病抗性基因研究进展

doi:10.16288/j.yczz.24-358

遗传 ›› 2025, Vol. 47 ›› Issue (5): 533-545.doi: 10.16288/j.yczz.24-358

水稻稻瘟病抗性基因研究进展

王占春¹^,²(), 钟桂涛¹, 张贝贝¹, 谢怡琳¹, 唐定中¹(), 王伟¹()

1.福建农林大学植物免疫研究中心，福州 350002
2.福建农林大学生命科学学院，福州 350002

收稿日期:2024-12-16 修回日期:2025-02-05 出版日期:2025-05-20 发布日期:2025-02-24
通讯作者: 唐定中，博士，教授，研究方向：植物与病原菌互作。E-mail: dztang@fafu.edu.cn；
王伟，博士，教授，研究方向：植物与病原菌互作。E-mail: vic_0214@163.com
作者简介:王占春，博士后，研究方向：水稻抗病育种。E-mail: zhanchunwang@foxmail.com
基金资助:
国家重点研发计划(2022YFF1001500);福建省自然科学基金项目(2024J09022)

Research advances in rice blast resistance genes

Zhanchun Wang¹^,²(), Guitao Zhong¹, Beibei Zhang¹, Yilin Xie¹, Dingzhong Tang¹(), Wei Wang¹()

1. Plant Immunity Center, Fujian Agriculture and Forestry University, Fuzhou 350002, China
2. College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, 350002, China

Received:2024-12-16 Revised:2025-02-05 Published:2025-05-20 Online:2025-02-24
Supported by:
National Key Research and Development Program of China(2022YFF1001500);Fujian Provincial Natural Science Foundation(2024J09022)

摘要/Abstract

摘要：

水稻(Oryza sativa L.)是我国重要的粮食作物，其生长发育过程经常受到稻瘟病的威胁，严重时导致巨大的经济损失。挖掘和利用水稻稻瘟病抗性基因，培育具有广谱抗性的优良品种是目前防治稻瘟病最经济有效的方法。稻瘟病抗性基因一般为编码含有核苷酸结合结构域(nucleotide-binding，NB)和富含亮氨酸重复结构域(leucine-rich repeat，LRR)的基因家族，也被叫做NLR基因，在水稻抗稻瘟病方面发挥至关重要的作用。因此，对NLR基因的挖掘以及阐明其与对应效应因子之间的识别和激活机制，对于培育抗病品种具有重要意义。本文对水稻中NLR基因的挖掘概况、NLR蛋白与稻瘟病菌效应因子之间的识别方式，以及成对NLR蛋白作用机制进行了总结和展望，旨在为水稻抗病育种提供参考。

关键词: 水稻, 稻瘟病, NLR基因, 抗性, 抗病育种

Abstract:

Rice (Oryza sativa L.) is an important food crop in China. Its growth and development are threatened by rice blast, which leads to huge grain losses in severe cases. Cultivating and deploying rice varieties that contain broad-spectrum resistance (R) genes is the most economical and effective strategy to prevent and control rice blast. In general, rice blast resistance genes code nucleotide-binding (NB), leucine-rich repeat (LRR) receptors (NLRs) that play a crucial role in the resistance to rice blast. Therefore, it is essential to clone NLR genes and elucidate the recognition and activation mechanisms between NLRs and effectors for rice disease resistance breeding. In this review, we summarize and provide perspectives on the research progress of NLR genes, the recognition between NLR proteins and effectors in rice, as well as the role and mechanism of paired NLR proteins in the resistance, hoping to provide reference for rice disease resistance breeding.

Key words: rice, rice blast, NLR gene, resistance, resistance breeding

王占春, 钟桂涛, 张贝贝, 谢怡琳, 唐定中, 王伟. 水稻稻瘟病抗性基因研究进展[J]. 遗传, 2025, 47(5): 533-545.

Zhanchun Wang, Guitao Zhong, Beibei Zhang, Yilin Xie, Dingzhong Tang, Wei Wang. Research advances in rice blast resistance genes[J]. Hereditas(Beijing), 2025, 47(5): 533-545.

图/表 2

表1

图1

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水稻稻瘟病抗性基因研究进展

Research advances in rice blast resistance genes

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NLR基因	年份	染色体	供体	参考文献
Pi37	2007	1	St. No. 1	[30]
Pish	2010	1	日本晴	[31]
Pit	2010	1	K59	[32]
Pi35	2014	1	Hokkai 188	[33]
Pi64	2015	1	羊毛谷	[34]
Pit1	2024	1	K59	[35]
Pit2	2024	1	K59	[35]
Pib	1999	2	IR24, BL1	[20]
Pib-Kr	2015	2	Krengosa	[36]
Pib-Sr	2015	2	Sercher	[36]
Pi-63	2014	4	Kahei	[37]
PiRP1	2020	4	日本晴	[38]
Piz-t	2006	6	Zenith	[39]
Pi9	2006	6	75-1-127	[40]
Pi2	2006	6	Jefferson	[39]
Pid-3	2009	6	地谷	[41,42]
Pi-25	2011	6	谷梅2号	[43]
Pi50	2012	6	Er-Ba-zhan (EBZ)	[44]
Pid3-A4	2013	6	A4 (普通野生稻)	[42,45]
Pid3-11/W3/W4	2014	6	Kasalath/Oryza rufipogon (100920/106046)	[42]
Pigm	2017	6	谷梅4号	[6]
Pid4	2018	6	地谷	[46]
Pizh	2019	6	ZH11	[47]
Pi9-Type3/4/5/6/9/10/11	2020	6	HCIH/PIIB/XS209/YD4038/THAVALU/ZWH210/R03138	[48]
Pi-36	2007	8	Q61	[49]
PibH8	2024	8	ZH11	[50]
BRG8	2024	8	Tetep	[51]
Pi-5/Pi-3/Pii	2009	9	Tetep	[52]
Pii	2013	9	Hitomebore	[53]
Pi56	2013	9	三黄占2号	[54]
LABR_64	2013	9	301279/312007	[55]
Pi-CO39	2002	11	CO39	[56]
Pik-m	2008	11	Tsuyuake	[57]
Pb1	2010	11	Modan	[58]
Pi54	2011	11	Tetep	[59]
Pik	2011	11	Kusabue	[23]
Pik-p	2011	11	K60	[60]
Pi-1	2012	11	LAC (根茎稻)	[61]
Pi54rh	2012	11	nrcpb 002	[62]
Pi54of	2014	11	nrcpb 004	[63]
Pik-h	2014	11	K3	[64]
Pike	2015	11	籼早143	[65]
Pia	2016	11	Aichi Asahi	[66]
Pikx	2019	11	NSFTV-131	[67]
Pikg	2021	11	Oryza rufipogon accession G9	[68]
Piks	2022	11	IRBLks-F5	[69]
Pb2	2022	11	Jiangnanwan	[70]
Pias	2022	11	WRC17	[71]
Pikps	2023	11	Shoni	[72]
OsBRW1	2024	11	C105TTP-4L-23	[73]
Pita	2000	12	Yashiro-mochi	[25]
Pijx	2023	12	XS134	[74]

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